Alvelac™— A Product Overview

Alvelac™— A Product Overview


Alvelac™ is a porous, osteoconductive, biocompatible and biodegradable synthetic scaffold that is synthesized from polylactic co glycolic acid (PLGA) and polyvinyl alcohol and produced using proprietary and patented technology. (Figure 1)

It is a rigid structure specifically designed to prevent collapse of the buccal and lingual walls in achieving width maintenance. It is strategically placed in extraction socket with the top of scaffold in line with the crest of the socket in order to raise the forming blood clot to that level thus achieving height maintenance.

The size of Alvelac™ does not occupy the whole socket thus allowing maximum space for blood to fill the socket. This allows for the patient’s own bone to form naturally within that space. (Figure 2)

The scaffold is designed with macro-channels and micropores for cell adhesion and nutrient flow as well as to provide necessary space for bone tissues to grow. The manufacturing process had enabled it to have additional properties of porosity and yet satisfy the strength requirements as porosity is needed for osteoblast from the socket walls to utilize Alvelac™ as a framework upon which to spread and generate new bone.

Alvelac™ ‘s crystallinity is adjusted in order to control the rate of degradation of scaffold in the socket to an optimal 2-6 months. This is to allow for the Alvelac™ enough time to maintain the socket integrity and yet dissolve away in time for bone to regenerate and not to obstruct its formation. Within a short period of time, patient’s own bone will form fully in the socket, achieving the speed of alveolar ridge preservation required by dentists to implement patients’ choice of prosthesis.

Material : Processed using Poly lactic co glycolic acid (PLGA) and polyvinyl alcohol Porosity : ~70% Pore Size/Channel Size : ~50 µm / ~2.4 mm
Dimensions : Available in various sizes (Figure 4)


This is a non-toxic, widely-used copolymer with strong mechanical adhesion to the surface of bone which suppresses bleeding and leads to enhanced haemostasis due to its rough surface and microporosities.  This material is approved by US FDA and is both biocompatible and biodegradable.

PLGA is a well established material which has been used extensively since 1970s in medical devices.  It is used in the manufacture of resorbable devices in craniomaxillofacial surgery in both pediatric and adult patients and hysterectomy procedures in women.  The material has also been used in orthognathic surgery involving the maxillary and mandibular regions of the jaw.  It is also a common choice in the production of variety of biomedical devices such as grafts, sutures, implants and prosthetic devices.

When in contact with blood or body fluids, it undergoes hydrolytic and enzymatic decomposition that results in production of two by-products, carbon dioxide and water, which are excreted via respiration or urine.  Since the body deals with these on a daily basis, there is virtually no adverse toxicological effects associated with using PLGA as a biomaterial.