About Us

Bio-Scaffold International (BSI), formerly known as Rapid-Tech Pte Ltd, was incorporated in Singapore, March 1999 to advance biomedical research. It focused on the development and manufacture of Poly Lactic Co-Glycolic Acid (PLGA) bio-scaffolds and tissue engineering. 

The initial work was in titanium mesh for use in cranioplasty. This was later switched to the development of bio-scaffolds for the regeneration of human tissues including bones, ligaments and joints.

In 2000, the company collaborated with NSTB, GINTIC to develop bio-scaffolds for use in Guided Tissue Engineering under the Local Enterprise Technical Assistance Scheme (LETAS) grant from SPRING Singapore. This resulted in the development of a new technology for the processing of bio-scaffolds. The first prototype was produced in December 2003 and a joint patent with A*STAR was filed with IPOS in respect of the new technology in 2004.

In April 2005, the company was awarded The Enterprise Challenge (TEC) grant by the Prime Minister’s Office for in-vitro and in-vivo testing on the bio-scaffolds with the Faculty of Dentistry (FOD), National University of Singapore (NUS). It also received the TEC Innovator Award in November 2005. Clean room facilities were set up for operations that year.

Histology results obtained from the in-vitro study at the NUS in August 2006 reported bone growth and mineralization inside and outside of the bio-scaffold implanted in the iliac of rabbits. The in-vitro and in-vivo tests were completed in November 2006.

ISO 9001 and ISO 13485 initiatives were launched in December 2006. The clinical trial commenced in June 2007 and was completed in November 2008. The clinical trial showed no signs of infection or other complications which can compromise patient safety. R & D facilities were established in June 2007.

In September 2007, a Memorandum Of Understanding (MOU) was signed with Saveetha University, India for the joint biomedical research in bone regeneration and dental implantology. The company subsequently received the Professional Enterprise (Prestige) Award with citation from Asian Management Association (AMA) in November 2007.

In September 2009, the groundbreaking bio-degradable bone regenerator, Alvelac™, beat 200 submissions from more than 40 countries to win the Poster Presentation award at the prestigious FDI Annual World Dental Congress (“FDI”) attended by 10,000 international participants. BSI’s invention represents Singaporean’s only entry in the year to have made it to the top 12 submissions amongst others from Japan, China, Taiwan, India, Poland, Iran, USA, Kazakhstan, Austria and many more.